Synthesis and Biological Activity of 1,3,4-Oxadiazoles Used in Medicine and Agriculture

Biologically active compounds play a key role in the fight against diseases affecting both human and animal living organisms, as well plants. Finding out about new molecules with potential biological effect, not yet described literature, is one of most important aspects development medicine agriculture. Compounds showing desirable activity include heterocyclic moieties such 1,3,4-oxadiazoles. The oxadiazole molecule composed two nitrogen atoms oxygen atom, forming five-membered ring. Structures this type have been successfully used treatment various humans animals, an modern It has proven that many derivatives exhibit antibacterial, antiviral, blood pressure lowering, antifungal, antineoplastic, anticancer, antioxidant, anti-inflammatory analgesic properties. In addition, based on 1,3,4-oxadiazole can act plant protection agents due to their herbicidal, insecticidal fungicidal activity. Due constantly growing interest systems nature, methods obtaining complex structures containing rings are sought. This article discusses synthesis exhibiting Based these techniques, could be future